This case report highlights the endothelial changes associated with emulsified silicone oil in a 77-year-old male patient. Five years following pars plana vitrectomy and intraocular silicone oil injection, the patient presented with multiple diffuse clear vesicles on the endothelium of his left eye, despite maintaining a clear and thin cornea. Specular microscopy revealed numerous small bubbles of emulsified silicone oil, along with mild endothelial damage.

The findings suggest that emulsified silicone oil can adhere to the corneal endothelium, resulting in a droplet-like appearance that may indicate endothelial pathology. This case underscores the importance of monitoring potential complications related to the use of silicone oil in ocular surgeries, particularly in terms of its effects on corneal health.

For further insights, the full report is available for review.